H2-calponin
WebDec 23, 2005 · Calponin is a family of actin-associated proteins first found in smooth muscle cells ().Three calponin isoforms (h1-, h2-, and acidic calponins) are encoded by three homologous genes. h1-calponin (2, 3) is specifically expressed in differentiated smooth muscle cells and has been extensively studied for its role in the regulation of … WebNov 27, 2013 · The level of HES-1 increased in cells cultured under a low tension condition, corresponding to the down-regulation of h2-calponin. h2-Calponin gene expression is further affected by the...
H2-calponin
Did you know?
WebAug 7, 2014 · The aim of the present study was to evaluate the use of calponin-h2 as a blood-based biomarker for the early diagnosis of this disease. Using two monoclonal … WebOct 1, 2003 · Calponin 2 (h2 calponin, CNN2) is an actin-binding protein implicated in cytoskeletal organization. We have found that the expression of calponin 2 is relatively …
WebWe describe the development of a preparative method to isolate molluscan catch muscle, calponin. This method is based on the ability of calponin to interact with actin in a temperature-dependent manner. After extracting thin filaments, as previously described, the extract was ultracentrifuged at 2 °C. While other surface proteins of thin filaments co … WebMar 29, 2024 · A Unique Downregulation of h2-Calponin Gene Expression in Down Syndrome: a Possible Attenuation Mechanism for Fetal Survival by Methylation at the …
WebAmong three isoforms of calponin, h2-calponin is found in both smooth muscle and non-muscle cells. The present study demonstrates that epidermal keratinocytes and … Calponin is mainly made up of α-helices with hydrogen bond turns. It is a binding protein and is made up of three domains. These domains in order of appearance are Calponin Homology (CH), regulatory domain (RD), and Click-23, domain that contains the calponin repeats. At the CH domain calponin binds to α-actin and filamin and binds to actin within the RD domain. Calmodulin, wh…
WebJul 8, 2024 · Calponin 3 (CNN3) plays an important role in regulating myogenic differentiation and muscle regeneration; however, the precise function of CNN3 in myogenesis regulation remains poorly understood. Here, we investigated the role of CNN3 in a knockdown model in the mouse muscle cell line C2C12. Methods
WebOur results suggest that the basic calponin gene product may be a novel prognostic variable in patients with osteosarcoma [1]. A unique downregulation of h2- calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21 [2]. cook county of corrections inmate searchWebMay 21, 2002 · h2-calponin associated with actin-tropomyosin thin fil-aments and caused an increased number of binuclear cells in which h2-calponin was concentrated in a nu … family care baselWebJan 1, 2003 · h2-Calponin is found in both smooth muscle and nonmuscle cells, and its function remains to be established. Western blots with specific monoclonal antibodies … family care beezcook county office hoursWebRT-PCR detected CNN2 transcripts in both cultured smooth muscle and nonmuscle cells and showed that mouse calponin h2 is expressed in embryonic and adult heart. CNN2 protein localizes to the cell-to-cell junctions of cardiomyocytes and … cook county of deeds in illinoisWebDec 23, 2005 · h2-calponin expression in epidermal keratinocytes. A, total protein extracts from mouse abdominal and footpad skin tissues were analyzed by Western blots using … family care beaufortWebDec 3, 2014 · calponin is an actin filament-associated protein reported in platelets, although the specific isoform expressed and functional role … family care basket