WebChromaSig: A Probabilistic Approach to Finding Common Chromatin Signatures in the Human Genome PLoS Comput Biol 4(10): e1000201. Posted on 2012/03/01 Author admin Categories Miscellaneous Tags ChromaSig, Chromatin, Signature. Leave a Reply Cancel reply. Your email address will not be published. Required fields are marked * WebApplying ChromaSig to a panel of 21 chromatin marks mapped genomewide by ChIP-Seq reveals 16 classes of genomic elements marked by distinct chromatin signatures. Interestingly, four classes containing enrichment for repressive histone modifications appear to …
Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed ...
WebOct 13, 2009 · ChromaSig: a probabilistic approach to finding common chromatin signatures in the human genome., UC San Diego. ChromaSig homepage An HMM approach to genome-wide identification of differential histone modification sites from ChIP-seq data. , Genome Institute of Singapore. WebOct 15, 2009 · We have recently developed a computational technique called ChromaSig to identify frequently occurring chromatin signatures (Fig. 3). Focusing on genomic regions with strong enrichment of histone modifications, ChromaSig employs a probabilistic approach to simultaneously align and cluster these regions to identify consistent signatures. bishop stories
ChAsE: chromatin analysis and exploration tool Bioinformatics ...
WebJul 4, 2016 · Abstract. Summary : We present ChAsE, a cross-platform desktop application developed for interactive visualization, exploration and clustering of epigenomic data such as ChIP-seq experiments. ChAsE is designed and developed in close collaboration with several groups of biologists and bioinformaticians with a focus on usability and interactivity. WebFeb 4, 2007 · Abstract. Eukaryotic gene transcription is accompanied by acetylation and methylation of nucleosomes near promoters, but the locations and roles of histone modifications elsewhere in the genome remain unclear. We determined the chromatin modification states in high resolution along 30 Mb of the human genome and found that … bishop stortford bid